Assoc. Prof.  Kosuke Ono


Department of Chemistry, School of Science

Tokyo Institute of Technology

2-12-1-H57 Ookayama, Meguro-ku, Tokyo 152-8551, Japan

E-mail: k.ono[at]


2004. 3

Tohoku University


2006. 3

2008. 1

The University of Tokyo

IBM Almaden Research Center



2009. 3

The University of Tokyo

Ph.D (DC1)

2009. 4

The University of Tokyo


2009. 6

University of California, Santa Barbara

Posdoc (JSPS)

2010. 3

Tokyo Institute of Technology

Assistant Professor (CREST)

2015. 4

Tokyo University of Science

Assistant Professor

2019. 8

Tokyo Institute of Technology

Associate Professor


2021    Yoshinori Ohsumi Fund for Fundamental Research

2020    Daicel Award in Synthetic Organic Chemistry, Japan

2020    Tokyo Tech Research Award

2020    SHGSC Japan Award of Excellence 2020

2007    Best Poster Award, The Young(-ish!) Giants of Chemistry, for Fraser Stoddart's 65th Birthday

2003    Poster Award, The 53th Conference of Japan Society of Coordination Chemistry

Research Project


Back cover.tif

Publication List

K. Ono, N. Iwasawa

“Oligoboroxine-based architectures”

J. Incl. Phenom. Macrocycl. Chem. 2021, ASAP.

​(Award paper)

• H. Takata, K. Ono, N. Iwasawa

“Controlled Release of the Guest Molecules via Borate Formation of  Fluorinated Boronic Ester Cage”

Chem. Commun. 2020, 56, 5613-5616.


• K. Tateno, K. Ono, H. Kawai

“Fluorescent Short-Stranded Helical Foldamers Based on L-shaped Dibenzopyrrolo[1,2-a][1,8]naphthyridine”

Chem. Eur. J. 2019, 25, 15765-15771.

​(Frontispiece, Synfacts 2020, 16, 0278.)


K. Ono, M. Niibe, N. Iwasawa

“A K+-promoted Diels-Alder Reaction by Using a Self-assembled Macrocyclic Boronic Ester containing two crown ether moieties”

Chem. Sci. 201910, 7627-7632.


K. Ono, N. Iwasawa

“Dynamic Behavior of Covalent Organic Cages”

Chem. Eur. J. 2018, 24, 17856-17868.

​(Invited paper, Concepts article, Frontispiece, Top 10% downloaded paper)


K. Ono, S. Shimo, K. Takahashi, N. Yasuda, H. Uekusa, N. Iwasawa

“Dynamic Interconversion between Boroxine Cages Based on Pyridine Ligation”

Angew. Chem. Int. Ed. 2018, 57, 3113-3117.

​(Back Cover)


• T. Uchikura, K. Ono, K. Takahashi, N. Iwasawa

“Utilization of Donor-Acceptor Interaction for Acceleration of the Catalytic Nucleophilic Addition to Aromatic Aldehydes”

Angew. Chem. Int. Ed. 2018, 57, 2130-2133.


• K. Tateno,R. Ogawa, R. Sakamoto, M. Tsuchiya, N. Kutsumura, T. Otani, K. Ono, H. Kawai, T, Saito

“Dibenzopyrrolo[1,2-a][1,8]naphthyridines: Synthesis and Structural Modification of Fluorescent L-Shaped Heteroarenes”

J. Org. Chem. 2018, 83, 690–702.​

​(Synfacts 2018, 14, 0479.)


• K. Ono, Y. Tohyama, T. Uchikura, Y. Kikuchi, H. Tkahagi, K. Fujii, H. Uekusa, N. Iwasawa

“Control of the Reversibility During Boronic Ester Formation: Application of the Construction of Ferrocene Dimers and Trimers”

Dalton Trans. 2017, 46, 2370–2376.​


• S. Ito, K. Ono, K. Johmoto, H. Uekusa, N. Iwasawa

“Switching of the solid-state guest selectivity: solvent-dependent selective guest inclusion in a crystalline macrocyclic boronic ester”

Chem. Sci. 2016, 7, 5765–5769.​


• S. Tamari, K. Ono, M. Hashimoto, T. Ozeki

“Control Over the Preference for Binding Sites of polyoxometalates to Silver Ethynide Cluster by Surface Charge Modification”

Dalton Trans. 2015, 44, 19056­–19058.​

(Front Cover)


• K. Ono, K. Johmoto, N. Yasuda, H. Uekusa, S. Fujii, M. Kiguchi, N. Iwasawa

“Self-Assembly of Nanometer-Sized Boroxine Cages from Diboronic Acids”

J. Am. Chem. Soc. 2015, 137, 7015–7018.​

(Science 2015, 348, 1329.)


• K. Ono, R. Aizawa, T. Yamano, S. Ito, N. Yasuda, K. Johmoto, H. Uekusa, N. Iwasawa

“Procedure-Dependent Construction of Two Kinds of Trimeric Self-Assembled Boronic Esters”

Chem. Commun. 2014, 50, 13683–13686.​


• Y. Kikuchi, K. Ono, K. Johmoto, H. Uekusa, N. Iwasawa

“Inclusion of Two Different Guest Molecules within a Rationally Designed Macrocyclic Boronic Ester in Organic Solvent”

Chem. Eur. J. 2014, 20, 15737–15741.​


• Y. Kikuchi, H. Takahagi, K. Ono, N. Iwasawa

“Enhancement of Host-Guest Interaction Using Rationally Designed Macrocyclic Boronic Esters with Naphthalene Core”

Chem. Asian. J. 2014, 9, 1001–1005.​


• S. Ito, H. Takata, K. Ono, N. Iwasawa

“Release and Recovery of Guest Molecules During the Reversible Gel Formation of Guest-Induced Macrocyclic Boronic Esters”

Angew. Chem. Int. Ed. 2013, 52, 11045–11048.​


• J. E. Poelma, K. Ono, D. Miyajima, T. Aida, K. Satoh, C. J. Hawker

“Cyclic Block Copolymers for Controlling Feature Sizes in Block Copolymer Lithography”

ACS Nano 2012, 6, 10845–10854.​


• S. Ito, K. Ono, N. Iwasawa

“Controlled Self-Assembly of Multiple Diastereomeric Macrocyclic Boronic Esters Composed of Two Chiral Units”

J. Am. Chem. Soc. 2012, 134, 13962–13965.​​


• N. Iwasawa, H. Takahagi, K. Ono, K. Fujii, H. Uekusa

“Guest-Induced Self-Assembly of Macrocyclic Boronic Ester Containing Diarylethene Units: Enhancement of Photoresponsivity”

Chem. Commun. 2012, 48, 7477–7479.​​


• T. Osuga, T. Murase, K. Ono, Y. Yamauchi, M. Fujita

“[m x n] Metal Ion Arrays Templated by Coordination Cages”

J. Am. Chem. Soc. 2010, 132, 15553–15555.

(Kagaku 2011, May.)


• J. Iwasa, K. Ono, M. Fujita, M. Yoshizawa, M. Akita

“Switchable trans-cis interconversion of an amphiphilic anthracene trimer”

Chem. Commun. 20095746–5748.


• K. Ono, J. K. Klosterman, M. Yoshizawa, K. Sekiguchi, T. Tahara, and M. Fujita

“ON/OFF Red Emission from Azaporphine in a Coordination Cage in Water”

J. Am. Chem. Soc. 2009, 131, 12526–12527.


• K. Ono, M. Yoshizawa, M. Akita, T. Kato, Y. Tsunobuchi, S. Ohkoshi, M. Fujita

“Spin Crossover by Encapsulation”

J. Am. Chem. Soc. 2009, 131, 2782–2783.


• K. Ono, M. Yoshizawa, T. Kato, M. Fujita

“Three-Metal-Center Spin Interactions through the Intercalation of Metal Azaporphines and Porphines into an Organic Pillared Coordination Box”

Chem. Commun. 2008, 2328–2330.

(Hot Paper, Synfacts 2008, 813.)


• K. Ono, M. Yoshizawa, T. Kato, K. Watanabe, M. Fujita

“Porphine Dimeric Assembly in Organic-Pillared Coordination Cages”

Angew. Chem. Int.Ed. 2007, 46, 1803–1806.

(VIP Paper, Inside Cover.)


• M. Yoshizawa, K. Ono, K. Kumazawa, T. Kato, M. Fujita

“Metal-Metal d-dinteraction through the Discrete Stacking of Mononuclear M(II) Complexes (M = Pt, Pd, and Cu) within an Organic-Pillared Coordination Cage”

J. Am. Chem. Soc. 2005, 127, 10800–10801.


• T. Fukuda, K. Ono, N. Kobayashi

“Specific Spectral Changes of Octaphenyltetraazaporphyrinatocobalt(II) in Response to Fluoride Ions”

Sci. Report Chem. (Tohoku Univ.). 2003, 80, 1–9.

• T. Fukuda, K. Ono, S. Homma, N. Kobayashi

“A Phthalocyanine Producing Green, Ocher, and Red Colors Depending on the Central Metals”

Chem. Lett. 2003, 32, 736-737.



• K. Ono

“Porous Organic Cage Crystals”

J. Syn. Org. Chem. Jpn. 2012, 70, 653-737.

• M. Yoshizawa, K. Ono, M. Fujita

“Molecules which pile up by themselves. New challenge to the next generation nano-technology”

Gendai Kagaku 2008, 453, 52-56.